Gene Edited Babies

Gene Edited Babies

by Deleted user -
Number of replies: 3

Gene editing has always been a controversial topic so Jankui must have known there would be some backlash to his research but still chose to continue with such. I think he was just behaving as a researcher but maybe did not acknowledge or care to acknowledge the possible consequences of doing such testing with little known about the side effects. An ethicist at the University of Oxford stated that “this experiment exposes healthy normal children to risks of gene editing for no real necessary benefit” (Normile 2018). I would have to agree with this scientist in that we do not have enough knowledge about gene editing to impose this science on healthy babies. I do understand in order for science to advance risks have to be taken but I think there are alternate ways of testing that could be executed before we begin testing on healthy humans. In fact, Jankui failed to provide any past scientific evidence on “preclinical research on mice and monkeys” (Li 2019) which gives little reason to his confidence to test on healthy humans. I think we can learn from this situation and require more evidence to be provided before this type of testing is performed on embryos. This situation could be compared to another unethical science trial being the Tuskegee Syphilis Clinical Trial, where scientists observed mostly black men with syphilis and did not give them proper treatment or tell them exactly what they were being treated for (CDC 2020). The victims of these two studies are very different, Tuskegee being men and Genetic testing being babies, but both of these victims did not consent to be tested on. The people in the Tuskegee trial were not fully aware of what was being done to them and the embryos/babies were too young to consent to be a part of an unethical trial. These types of trials may make people feel distrust with the medical community and lead to people being afraid to be treated for their medical problems because they are afraid to be disrespected and experimented on.  

CDC. (2020, March 2). Tuskegee Study - Timeline - CDC - NCHHSTP. Retrieved from https://www.cdc.gov/tuskegee/timeline.htm

Li, J. (2019). Experiments that led to the first gene-edited babies: the ethical failings and the urgent need for better governance. J Zhejiang Univ Sci B. 20(1): 32-38. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331330

Normile, D. (2018). CRISPR bombshell: Chinese researcher claims to have created gene-edited twins. Science mag. Retrieved from https://www.sciencemag.org/news/2018/11/crispr-bombshell-chinese-researcher-claims-have-created-gene-edited-twins


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In reply to Deleted user

Re: Gene Edited Babies

by Deleted user -
Hey Evie, in reading your forum you have brought up a lot of good points. I found it interesting in one of the studies you quoted from Normile, in that I didn’t realize that it could have a negative effect on healthy babies. From reading other articles I thought it would benefit them a fair amount considering they would be resistant to the HIV. I think your points can be seen in two ways in that what he did wasn’t right and it is risky without him having done any previous studies on monkeys or other animals. However, I do think that risks need to be taken in order to advance modern science and I’m not saying he did the right thing but I feel like he helped out the scientific community greatly knowing that this can work.

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In reply to Deleted user

Re: Gene Edited Babies

by Deleted user -
Hey Evie,
I agree with a lot of issues that you discussed in your forum. I agree with you that the experiment had no real necessary benefit to the babies except that it gave the researcher proof that it could be done. I do think that maybe they should have tested on something other than healthy human babies. I think it is crazy how there was no consent on the two experiments you compared. I think that is a main concern because as a researcher you are risking a person's life, and in this case it was healthy babies lives being risked. I also said that these experiments could lead people to deny medical attention or tests when they really need it because they will become scared that not all the risks are being explained to them.

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In reply to Deleted user

Re: Gene Edited Babies

by Deleted user -
Hey Evie,
I enjoyed reading your response on gene editing babies. I think Jankui didn't think all the way through the experiment, I think he was just so focused on the outcome that he overlooked the risks and complications. I agree with you when you say this experiment had no benefit to the babies other than to prove that it could be possibly be done. I don't think they actually cared about how the experiment would react the the babies or even the parents. A lot of our classmates spoke about the Tuskegee Syphilis Clinical Trail. Me personally I didn't write about that specific trail I wrote about Henrietta Lacks. The Tuskegee Syphilis Trail was very unethical. With this study , I didn't like how they treated the black men were treated and how they wasn't allowed to get the right treatment for syphilis.

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